Endocrine Abstracts

An empty sella (ES) develops when cerebrospinal fluid (CSF) compresses pituitary tissue until it lines the sellar floor and walls and lead to shrinkage of pituitary gland. Primary ES occurs when CSF enters the sella from the subarachnoid space that may or may not be associated with increased intracranial pressure. Secondary ES is a result of an injury to the pituitary itself (e.g. pituitary apoplexy) or the consequence of surgical or radiation treatment. Primary ES is most com...

A 22-year-old man presented to the Endocrinology unit for short stature. His height is 1.53 cm; weight is 38.5 kg. Physical examination revealed short stature, lean body mass, low-set ears and a short fifth finger on the right. His bone age were consistent with 19-year. He had a history of undescended testis operation at 5-year old and history of strabismus surgery at 14-year old. He had a delta f 508 heterozygote mutation with normal sweat test. His biochemical analysis excep...

Blood flow obstruction through superior vena cava leads to superior vena cava syndrome (VCSS). The most common cause of the VCSS is malignancies. Enlargement goitre is an unusual cause of VSSS. A patient with superior vena cava syndrome secondary to enlarged thyroid gland was presented in this case report. An 84-year-old man presented to endocrinology unit with gradually increasing neck mass, dysphagia, and shortness of breath. His physical examination revealed webbed neck wit...

A 17-year-old girl was referred to Endocrinology Unit by her neurosurgeon. She had complained of severe headache, palpation induced galactorrhoea on left mammary and visual abnormalities for 1–2 months. Her menstrual period was regular. On physical examination a pale face and fatigued appearance was noticed. Biochemical and hormonal analyses are as follows: fasting glucose level was 84 mg/dl, serum sodium level was 140 mmol/l (136–145), serum potassium level was 3.9 ...

Extraadrenal perirenal myelolipom has been reported since 1980. In recent years, it has been reported at an increasing rate in different sites of the body ranging from the nasal cavity, mediastinum to presacral, paravesical region. However, it was the first reported case that perirenal multiple myelolipomas, each myelolipomas was about 5 cm in diameter, in associated with cortisol hypersecretion. A patient was an emigrant. She was followed in her country and was prescribed ket...

Aim: The etiology and underlying pathology of non-functional adrenal adenoma has not been clearly defined, yet. Blood pressure levels according to adrenal adenoma size has not been evaluated, yet. Therefore, we evaluated 24 hour ambulatory blood pressure levels in patients with non functional adrenal adenoma.Materials & Methods: We studied thirty newly diagnosed adrenal adenoma patients in a tertiary health-care center. They grouped in two categories...

Objective: The aim of the present study was to evaluate cardio metabolic risk factors in patients with non-functional adrenal adenoma.Materials and methods: We studied thirty newly diagnosed adrenal adenoma patients and 30 healthy participants. Fasting glucose, insulin, lipid, hormone profile were evaluated from each patient.Results: The frequency of diabetes mellitus and hypertension were statistically higher in adrenal adenoma gr...

Introduction: Ectopic adrenocorticotropic hormone (ACTH) syndrome is characterized by hypercortisolism due to the hypersecretion of non-pituitary ACTH-secreting tumor leads to the Cushing’s syndrome. Herein, we present a case with Cushing’s syndrome, which is diagnosed ACTH-secreting renal malignant paraganglioma.Case: A 40-year-old woman presented with a 5 month history of newly diagnosed hypertension and diabetes, weakness, hyperpigmentation,...

Background: Subclinical hypothyroidism is a thyroid disease which encountered in practice, commonly. Thyroid hormones affect metabolic syndrome parameters including HDL cholesterol, triglycerides, plasma glucose levels, blood pressure and abdominal obesity. Furthermore; there have been growing evidences about the relationship between vitamin D deficiency and autoimmune thyroid diseases. Therefore; we aimed to evaluate the association between the metabolic parameters and 25-OH-...

Background: Insulin resistance and diabetes mellitus are associated with decreased serum vitamin D level. Therefore, we evaluate the 25-OH-vitamin D in GDM. This study was performed to evaluate the serum vitamin D levels in GDM patients.Methods: This study consisted of 38 patients with GDM who followed up in Haseki Training and Research Hospital’s Endocrinology outpatient clinic. GDM was diagnosed with 50 g (if postprandial 1 h >130–199 mg/...